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The answer lies in The actual fact that there are a number of isoforms of each troponin subunit which are encoded by unique genes, a few of that happen to be expressed selectively in cardiac muscle. Whilst TnI and TnT have distinctive cardiac and skeletal isoforms, they share a standard isoform of TnC: the gradual-twitch skeletal muscle mass isofor

The variances in AA sequences permitted enhancement of quantitative assays for cTnI/T. Most cTn assays are non-aggressive enzyme-connected immunosorbent assays (ELISA) based upon the sandwich principle, making use of the higher specificity and affinity of antibodies.31 The assay relies on the seize antibody which binds to a specific epitope of cTn,

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